Archive for October 26th, 2009
Gaucher Disease treatment: An Alternative
Gaucher disease has become a serious treat to the community nowadays. Even though there are several available treatments to it, the main issue is the cost. Not many people afford to pay the treatment cost. Therefore, looking for an alternative cheap and effective treatment is the main interest of the researchers.
One of the ‘proven working’ treatment is by using enzyme theraphy or specifically using Cerezyme (TM). Amongst the step used in the enzyme theraphy is by using the beta-glucosidase in the inhibitory process. One novel idea is, if we can produce or design a new cheap enzyme to run the inhibitory process by some prosess in the active site. But another novel idea just pop up if we used the reverse process of designing the inhibitor rather than designing the new enzyme.
The idea seems to be good. If we can design such a strong inhibitor (or just search for it), we can reduce the amount of enzyme use for the inhibitory process as well as the amount of inhibitor; thus can reduce the overall cost. We shall see the progress of searching those cheap enzyme and new inhibitors development in shorter time by the advancement of the medical research now. Hopefully those research can be done faster, because the need of efficient and low cost treatment is the priority nowadays.